Journal: Epidemiology Research International

Article Title: The Mississippi Delta Cardiovascular Health Examination Survey: Study Design and Methods

doi: 10.1155/2014/861461

Figure Lengend Snippet: Mississippi Delta Cardiovascular Health Examination Survey specimen collection and processing.

Article Snippet: 3 and 4 , EDTA Lavender top (4 mL) , No spin , None , Whole blood , Cold , LabCorp , Hemoglobin A1c; complete blood count.

Techniques: Clinical Proteomics

Journal: bioRxiv

Article Title: Robust and High-Throughput Analytical Flow Proteomics Analysis of Cynomolgus Monkey and Human Matrices with Zeno SWATH Data Independent Acquisition

doi: 10.1101/2022.11.30.518440

Figure Lengend Snippet: Volcano plots representing differential proteins in individuals diagnosed with non-alcoholic steatohepatitis (NASH, n = 20) ( A ) and type 2 diabetes (T2D, n = 10) ( B ) in comparison to healthy individuals (n = 20). A two-sided Welch’s t-test was used for differential analysis and proteins with FDR < 0.1 were considered significant. Proteins underlined and in bold are uniquely significant in Zeno SWATH mode. ( C ) Pie charts representing the proportion of significant proteins (FDR < 0.1) in Zeno SWATH DIA mode that were i) not detected, ii) detected and significant, and iii) detected but not significant in SWATH DIA mode. ( D ) Comparison of pathway significance using significant proteins identified in SWATH and Zeno SWATH DIA modes in NASH and T2D studies. Ingenuity Pathway Analysis was used for enrichment analysis and pathways with P-values < 0.05 were considered significant.

Article Snippet: Commercial human EDTA-plasma samples from 20 individuals self-reported as healthy were purchased from BioIVT and EDTA-plasma samples from 20 individuals diagnosed with NASH, and 10 individuals diagnosed with T2D were purchased from ProteoGenex (lot numbers and subject demographics information are available in Table S4 ).

Techniques: